Practical Stereological Methods for Morphometric Cytology

P-145: Efficacy of Simvasiatin in The Prevention of Doxorubicin-Induced Testicular Morphometric-Stereological Alterations in Mice

Background: Doxorubicin (DOX), a widely used antineoplastic compound, is associated with testicular damage and infertility. In this study, we intended to determine the possible preventive effects of simvastatin (SIM), a lipid lowering agent with antioxidant and anti-inflammatory activities, on testicular morphometric-stereological changes due to DOX treatment in mice. Materials and Methods: Mal...

A review of recent developments and applications of morphometry/stereology in lung research.

Design-based stereology is the gold standard of morphometry in lung research. Here, we analyze the current use of morphometric and stereological methods in lung research and provide an overview on recent methodological developments and biological observations made by the use of stereology. Based on this analysis we hope to provide useful recommendations for a good stereological practice to furt...

The effects of bortezomib on the ovariectomy applied rat uterus: A histopathological, stereological and immunohistochemical study

Objective(s): In this study, potential protective effects of Bortezomib (Bort), as a proteasome inhibitor, were investigated on the uterus of ovariectomized rats by histological, morphometric and immunohistochemical methods.Materials and Methods: In this study, 18 Sprague dawley strain female rats (12 weeks old, 250-300 g body weight) were used. Animals in the control group (Cont, n=6) were not...

How much is there really? Why stereology is essential in lung morphometry.

Quantitative data on lung structure are essential to set up structure-function models for assessing the functional performance of the lung or to make statistically valid comparisons in experimental morphology, physiology, or pathology. The methods of choice for microscopy-based lung morphometry are those of stereology, the science of quantitative characterization of irregular three-dimensional ...

The set of stereological morphometric grids macros for ImageJ software